細胞治療のための超並列単一細胞加工技術の開発

抄録

It is expected to develop and advance treatments for diseases such as hematologic and solid cancers that have been difficult to treat with existing pharmaceuticals. The use of pharmaceuticals based on genetically engineered cells and macromolecules, rather than conventional low-molecular-weight compounds, is rapidly advancing. To spread these therapies, several issues must be resolved. Specifically, the elucidation of disease biology, the establishment of drug safety, and cost reduction are necessary. The challenges include the complexity of cells, their fragility, and a large amount of processing involved, which are difficult to solve based-on conventional engineering alone. We try to solve these problems and work on the following two technologies: (1) autonomous drug discovery using disease models and (2) processing and screening of more than 100 single cells. In this presentation, I will present the status of our laboratory's works.