MEMSによる細胞の機械特性計測とマニピュレーション

抄録

Mechanical properties of cells relate to their growth, such as differentiation and cell mortality, and represent the diseases. Investigating the mechanics of cells will contribute to the diagnosis and the study of regenerative medicine. Multiple properties of cells should provide more broad and precise information to us. We evaluated cell mechanics and gene expression analysis using MEMS tweezers, which can characterize and manipulate single suspended cells. To characterize adherent cells, we developed MEMS with a single probe and validated the device. Call trapping and manipulation of the measured adherent cells were also examined using MEMS tweezers.