651 骨再生シミュレーションを用いた Scaffold の三次元ポーラス微視構造の最適設計

抄録

The establishment of the designing method for the initial scaffold structure is required for the appropriate property of bone-scaffold system in bone regeneration process using scaffold. In this study, the optimization method of the microscopic structure of scaffold was investigated by 3D computational simulation of bone regeneration. Two types f initial structures with lattice and spherical cavity and different volume fraction were simulated. Simulation results were evaluated quantitatively using the proposed evaluation functions. The optimum structure and the validity of this method were discussed from the viewpoint of mechanical functions of bone-scaffold system.