Pulsatile Flow and Deformation in Curved Stenosis Models of Arterial Disease

Abstract

There are complicated forces involved in the stenosis, which may causes the atherosclerotic plaque fracture. The increase in blood flow velocity in the post stenosis causes negative transmural pressure, which may compress the plaque to collapse. We used experimental stenosis models that closely approximate the arterial disease situation where the entire stenosis is compliant. This paper was examine the influence of curvature and stretch of the stenosis on flow and collapse under pulsatile flow.