To secure occupant safety is one of the most important factors in vehicle design. To evaluate occupant safety, the injury indexes of dummies are defined by regulations. Dummy kinematics is so complicated: that many vehicle parameters affect the injury indexes. Balancing the characteristics of the restraint systems is a multi-objective, multi-parameter optimization. Generally the injury indexes show linearity in relation to the parameters of the restraint systems. However, a discontinuous boundary exists in which airbag bottoming out causes a peaky reaction force. This paper proposes a DOE (Design of Experiment)-based optimization method that eliminates this discontinuity and provides a high-fidelity response surface model An optimized result obtained with the response surface model was certified by simulation.