抄録
The morbidity of osteonecrosis of the femoral head (ION) has grown rapidly. An essential ION treatment is to prevent collapse of a degeneration site on femoral head with necro-cytosis. The biomechanical degeneration of trabecular bone structures has been few documented while regenerating processes of bone tissue and fibrous tissue have been shown to lead the structural degeneration. The purpose of this study was to evaluate the relationship between the trabecular architecture and the degree of mineralization of bone (DMB) using micro-CT image data in the necro-cytosis area. ION was surgically induced in the left femoral head of Wistar rat which were analyzed by morphometric evaluation data and DMB parameters after 1,3,6 weeks postoperation. We conclude that significant increasing in bone volume (BV/TV) and trabecular thickness (Tb.Th) after ION may lead to an increase in the structural and mechanical strength. This suggests that bone tissues after ION may regenerate by pathological bone repair, so called additional bone formation, and that there is still necrotic-cytes tissue.
