512 固体基板上における蛍光標識リゾチームの1分子観察と分子動力学シミュレーション(J01-3 計算生体力学におけるマルチスケール・マルチフィジックス問題(3),J01 計算生体力学におけるマルチスケール・マルチフィジックス問題)
詳細
Proteins play various roles in a living body. If those highly functional substances can be used as materials, they could be industrially applicable to various uses. For that purpose, it is necessary to elucidate interactions between proteins and inorganic matters, but there are many still unknown points. In this study, in order to understand the interactions, we have done real-time single molecule visualization of fluorescence labeled protein (rhodamin labeled lysozyme) on inorganic substrates by using the fluorescence microscope and succeeded in these observations, for the first step. These results are compared and examined with those of molecular dynamics simulations, and we aim at establishment of computer simulation technology in this field.
