This paper describes the prediction of index of thrombus formation in shear blood flow by computational fluid dynamics (CFD) with Lattice Boltzmann Method (LBM), applying to backward facing flow, which is simple model of turbulent shear stress in the high speed rotary blood pumps and complicated geometry of medical fluid machines. Assume that blood is multiphase fluid, blood plasma and red blood cell. From the computational data of multiphase fluid of backward facing flow, the thrombus formation (thickness) is estimated.