When the human head is loaded by the translational acceleration in the traffic accident, the human brain is damaged at the crash side and the counter side (i.e., coup and contre-coup brain injuries). The purpose of this study is to investigate a generation mechanism of coup and contre-coup brain injury and to develop a prediction method of the brain injury at the nerve cell level by using the finite element method (FEM). We carried out a multi-scale crash simulation by using a macroscopic head model and a microscopic nerve cell model. We investigated the hydrostatic pressure distribution in nerve cell. The results show the availability of our multi-scale analysis.
