Direct numerical simulations(DNS) of turbulent channel flow of surfactant solution are carried out, in order to reveal the mechanism of drag reduction by the effect of surfactants. The intensity of the streamwise vortices in surfactant solution is smaller than that in Newtonian fluid, although the streamwise component of velocity fluctuation is maintained. The results show that the effect of surfactant suppresses the distribution from the streamwise component of turbulence energy to the spanwise and the wall-normal components. In addition, large-eddy simulations(LES) with the Smagorinsky model are carried out in the flow field of surfactant solution. The results of LES are not corresponding to those of DNS.