The objective of this study was to clarify the muscle load in carrying an infant by the computer simulation. In order to obtain the input data for the simulation model, joint angles, electromyograms, and the force to segments in carrying an infant were measured in the experiment. Comparing the measured electromyogram data with the analyzed data by the musculoskeletal simulation, similar tendencies were obtained with respect to the muscle activities of Trapezius and Elector Spinae. From the results, it was found to be possible to reduce the physical load by selecting the appropriate carrying method according to the change in the simulation.