抄録
Titanium and its alloys are widely used as metallic biomaterials because of their high resistance to corrosion and biocompatibility. However, titanium ion is sometimes detected in tissues around titanium implants. The cause of ion release may be related to some kinds of organic species such as Macrophages. The aim of the present study is to clarify the effect of the existence of Macrophages on corrosion response of metallic implants. Immersion tests of highly polished SUS316 disks were carried out using 4 types of medium; RPMI1640+FBS(solution A), RPMI1640+FBS+U937(solution B),RPMI1640+FBS+Macrophages(solution C) and Ringers solution (solution D). All tests were performed at 37℃ in normal environment with 5% CO_2 added. To measure the corrosion rate, electrochemical tests were also carried out.
