Abstract
There are emerging needs for the manipulation of cellular functions of high-value added cells, which requires such technique as physical handling in single cell level, introduction of foreign substances, measurement of the cell response, fusion, factor exchange among cells, etc. Nanotechnology, based on microfabrication is expected to have high potential in this field. In this paper, our recent research topics, such as on-chip electroporation, electrofusion, and their application to the measurement and alternation of cellular functions, cytosol transplants, are presented.
