Abstract
Photodynamic therapy (PDT), which is able to destroy tiny lesions to minimize tumor recurrence and also remove target tumor part very precisely, has been extensively investigated. There are two main endoscope techniques at present, laser fiber separated from endoscope and endoscopic palliative techniques. However, the use of former method renders larger operative incision, and the latter endoscope provides a view field which is different from the laser irradiation field. To solve the problem, in this paper, we propose a novel flexible coaxial laser endoscope system for PDT, which is able to provide image and transmit laser to object target simultaneously. In this system, a flexible imaging fiber bundle is applied for its coherent light guiding. The visible light is transmitted into flexible imaging fiber bundle, reflected by polarizing beam splitter, then camera catches the image. And at the same time diode laser for PDT passes through the beam splitter into imaging fiber bundle. After traversing fiber bundle, the laser irradiates object target. In the experience, we give the results to evaluate the endoscope image, and also measure the laser power loss from laser fiber to endoscope header.
