Abstract
In this study, we developed a cell stretching micro device for in situ observation of cellular response to stretch loading. In studies that using conventional observation apparatus only investigate the cellular response which slowly arise (ex. in minutes, hours, days) aster stretch loading. Our device is fabricated by applying the MEMS technique. We demonstrated the performance of the device. Rigid displacement of the cell body during stretching loading was well suppressed. We conducted a real-time in situ observation of single osteoblastic cell and evaluated the cellular response to stretch l.
