Recently, optimization becomes more important in various fields. The structural optimization by using genetic algorithms has been developed and applied to various kinds of products such as cathode-ray tubes, laser beam machines and cellular mobile telephone flips. A new optimization system that works on personal computers is developed so that engineers can use the optimization technique easily. This optimization system can handle several optimization techniques such as P-GA, FSD, SA and RSM. Furthermore, it is applicable to multiple fields optimization, for example, structural analyses, thermal analyses, vibration analyses and control analyses. This paper presents applications of the optimization system to structural optimization of products such as a three-dimensional laser beam machine, a cellular mobile telephone flip and a stator of a wind turbine generator Moreover, each optimization result of P-GA, FSD, SA and RSM is examined and discussed in detail, and a guideline to choose an optimization technique corresponding to optimization problems is proposed.