Gas-liquid two phase flows are common in industrial processes that require high mass transfer rates and chemical reaction rates. Bubbles of 2-3 mm diameter take the highest mass transfer coefficient k_L. The physical phenomena of those bubbles are more complex than those of small spherical bubbles due to the following reasons; they ascend zigzag or spirally even in stagnant water; in addition the zigzagging bubbles shed a characteristic vortex (i.e. horse-shoe-like vortex). The relation between the mass transfer and the curious bubble motion is still unknown. It is important for well understanding of the mass transfer mechanism, but has not yet been investigated. In this research, we discussed the relation and concluded that the bubble surface motion and gravity-center motion and ambient liquid play a great role in the mass transfer.