Abstract
Natural cellular activities are increasingly exploited for micro analytical systems, biochemical reactors. Novel use of pulsating heart cell as mechanical micro actuators has been developed in our group. For example, micro pomp using cardiomyocyte sheet. This study aims at the development of a muscle block where the sheet is enhanced to three dimensions using Parylene. If we can make the pulsating muscle block, there are some advantages such as various structures can be made by assembling, and process it to easy-to-use shape according to the purpose. In addition, to strengthen the contractile force of muscle cells, it is necessary to expand and contract muscle cells by physical stimulation. We will develop the device that can stretch muscle block in three dimensions. We developed prototype of parylene three dimensional structure and stretching system and did some experiments about them.
