Abstract
Motor proteins, biomolecular machines, have been successively integrated into microdevices such as MEMS and lab-on-a-chips. For successful integrations, guiding of cytoskeletal filaments is one of key issues. The guidings can be achieved with microfabricated substrates or by imposing external force to the microtubules. Here, we present a computer simulation which reproduces the guidings of microtubules propelled by kinesin motors.