The Proceedings of JSME annual Conference on Robotics and Mechatronics (Robomec)
Online ISSN : 2424-3124
2017
Session ID : 1P1-N11
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Effect of Cell Exercise by hydrostatic pressure
*Atsushi KIRIMOTOHiroaki ITOMakoto KANEKOMitsuhiro HORADE
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Abstract

Cellular tissue made of smooth muscle cells becomes stiffer after applying cyclic pressure during the culture, and we call the procedure of applying such cyclic pressure as “Cell Exercise”. In conventional approaches, the pressure is applied using pressurized air, and consequently, the carbon dioxide in the air dissolve into the culture solution and changes the pH in the solution. The goal of this study is to create a system that keeps pH stable in the culture solution. We propose a method of applying pressure by hydrostatic pressure instead of pressurized air to avoid changing the pH of the solution. Based on the experimental results, we show that this method is sufficient to perform Cell Exercise.

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© 2017 The Japan Society of Mechanical Engineers
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