Host: The Japan Society of Mechanical Engineers
Name : [in Japanese]
Date : June 05, 2019 - June 08, 2019
Recently, muscle tissue and cells have received much attention as novel actuators due to their superior characteristics as actuators. Many research groups fabricated tissue engineered muscles with C2C12 myoblast cells in vitro. In spite of their struggles, the muscle tissues reported so far can generate force less than 1/10 of native muscle tissues in a living body. This study develops an automated culture system which can automatically apply electrical stimulation and replace medium and evaluates contractile force of muscle tissues. As a result, electric stimulations appropriate for muscle cells increased contractile force of tissue engineered muscle. This result suggests that the developed system is able to improve tissue engineered muscle.
