Less-invasive Photo-irradiation Cell Patterning in GelMA for Massively Parallel 3D Cell Assembly

Abstract

This study aims to create a disease model that mimics the microenvironment of a cancer, which is useful for drug discovery and elucidation of biological functions. Using a digital mirror device, cells were fixed in gelatin methacrylate (GelMA) by light irradiation. We report the results of exploring minimally invasive cell placement conditions based on cell viability and time-lapse observation.