Host: The Japan Society of Mechanical Engineers
Name : [in Japanese]
Date : June 06, 2021 - June 08, 2021
In recent years, cell spheroids have been attracting large attention for their applications in drug efficacy evaluation or tissue engineering for organ and blood vessel regeneration. In our study, we proposed a method to fabricate cell spheroids using vibration-induced flow for easy recovery and mass production. However, due to insufficient design of the generated flow pattern, the produced cell spheroids varied in size and shape. In this paper, we discuss designs of micropillars for vibration-induced flow to improve the reproducibility of cell spheroid production. By using a new design of pillars, we succeeded in formation of cell spheroid. And then, we considered effect on formation of cell spheroid by a vortex flow at the center of micropillar array with vibration-induced flow.
