Development of a multimodal stimulus measurement system for evaluation of cellular response based on microhand

Abstract

In recent years, with the development of the life science field, there has been an increasing demand for the measurement of the properties of cells and tissues. In particular, various techniques have been proposed to measure the response of specific cells to various external stimuli, in order to realize unprecedented analysis. In our laboratory, we are developing a small microhand system that can approach cells with dexterity and speed. Furthermore, we have been developing a new end-effector based on this microhand technology to extend the system to various stimuli such as chemical and temperature stimuli as well as force stimuli. In this paper, we report on the development and evaluation of a micro hand end-effector for multimodal stimulation such as local chemical stimulation as well as force stimulation.