Abstract
In this paper, molecular behavior simulations considering non-intrusive two laser measurements were performed to investigate the influence of the heat from the laser. Virtual particle was released into microchannel and particle trajectory was changed at nanoscale by the heat from laser. In microscale laser measurement concentration distribution by simulation had no change with the heat from laser. However, only in nanoscale imaging, Raman scattering intensity from the virtual particle was increased because of the virtual particle behavior. The influences on molecular diffusion phenomena in nano/microscale by the heat of the laser were successfully explained.