抄録
In an effort to utilize saccharide-iron oxide nanoparticles in medicine, we synthesized the magnetic particles coated with various types of saccharides using a coprecipitation method. The effects of various coating materials (saccharides) and conditions for their synthesis on the magnetic properties and particle diameter were investigated. All synthesized samples presented superparamagnetic behavior. Magnetic properties of saccharide-iron oxide nanoparticles were mainly dependent on the pH conditions during their synthesis. There was an adequate pH condition at which high magnetic property can be obtained. The size of the colloids could be controlled by a well-chosen temperature during synthesis and concentration of saccharide solution. Moreover, the type of saccharide coating had a significant effect on the size of the colloids and their magnetic properties. Magnetic particles coated with polysaccharides showed higher magnetization than those coated with low-molecular saccharides, and the diameter of colloids coated with polysaccharides was larger than that of those coated with low-molecular saccharides. The ultimate saturation magnetization was 24.0 [A·m2/kg], and the mean diameter of colloids could be controlled in range of 74.5 [nm]–455.1 [nm].
