Abstract
In the previous paper, the author reported that cuttle fish oil heat-polymerized in a stream of CO2 for 10 hours at 250°C, was toxic to rats and that the cyclic ethyl ester separated from the this treated oil by the method of urea-adduct forming process was highly toxic to rats while the straight chain ethyl ester non-toxic. In this paper, quite the similar results are presented on cuttle fish oil polymerised by heating in the presence of the air for 10 hours at 225±10°C.
The oil contains a quite small amount of peroxide, but exerts a strong toxic action to rats due to cyclic ethyl ester brought about by polymerization.