Abstract
The influence of bile and bile acid on the absorption of insoluble calcium salts, in theb owel was observed.
The results obtained were as follows:
1) In vitro, calcium phosphate was dissolved by bile in pH6.0, but fatty acid calcium was not dissolved, and the inhibiting effect of bile and bile acid on the production of fatty acid calcium was not observed.
2) In vivo, by the isolated bowel of the dog, the absorptivities of calcium salts, which have high or low solubility in the bowel were observed.
a) The absorption of CaCl2and Ca was promoted by bile and taurocholic acid.
b) The Ca stearate seems to be slightly absorbed by the supplementation of some bile.
c) The Ca oleate and Ca carbonate were not absorbed without regard to the presence of bile and taurocholic acid.
3) The absorption of Ca chlorate seems to be promoted in the pregnant dog.
