Abstract
When the rats were fed with “high Ca, low P, vitamin D free, composite feed (Ca/P 5: 1 or P 0)”, they suffered from experimental rickets. The authors observed the histological changes of tooth and bone of those rickety rats and found the existence of interference with the calcification of dentin similar to that seen in typical rickets.
The addition of small amounts of V. D, i. e., 1 or 2 I. U. per day to thefeed of a rickety rat over a period of 14 days brought about the production of wellcombined calcosperits in the calcified layer of dentin, but no marked formation of calcosperits was found in the epipyseal portion of the shin bone.
