Abstract
For the purpose of exploring the effects of diet on arteriosclerotic disease, changes in serum protein and compound protein by diet were observed in normal men and. rabbits mainly by means of paper electrophoresis with the following results:
1. Higher carbohydrate diet produced changes (an increase) in the α2-glycoprotein fraction, while higher fat diet caused changes in the β-and γ-lipoprotein fractions.
2. The total protein-bound carbohydrate level was not so profoundly influenced by such diet. The cholesterol level was increased by higher fat diet. No increase in the blood sugar level was caused even by higher fat diet in the case of a short period. Rather the blood sugar level increased by higher fat diet.Impairment of Langerhans' islands by fat diet was suspected. These findings also show serological features which seem to indicate liver impairment.
3. Changes in serological findings were connected with being accustomed to diet.
