Abstract
The effect of mucin on the amino acid absorption in the small intestine of rat was studied through the perfusion technique.
A 10cm section of the intestine was separated about 7cm apart from the pylorus at the upper end, and connected to the circulation system. The perfusion solution containing 2μM amino acid was circulated through the system, at the rate of 0.7ml per min. at 37°C.
Chemical analyses of the residual amino acids in the perfusing solution showed that, in the presenceof 0.005% of mucin, the increase in absorption by the small intestine was observed in the following 8 amino acids, alanine, valine, leucine, proline, serine, methionine, aspartic acid and arginine, in comparison with the control system devoid of mucin.
