Abstract
A study on calcium metabolism in the blood of cases of malignant tumor revealed a decrease in serum ionic calcium and an increase of magnesium The changes are more pronounced as the disease becomes more severe.
Sesame oil, rapeseed oil, calcium mesotartrate and vitamin K5, with the action of increasing serum ionic calcium and decreasing magnesium and inorganic phosphate, were given to mice transplanted with Ehrlich ascites tumor cells, to study the body weight curve, effect of life prolongation, changes in components of ascites and number of tumor cells, in relation to serum ionic calcium.
Body weight curves were not remarkably different from controls upon vegetable oil administration. However, the groups given sesame oil and rapeseed oil showed a slight prolongation of the survival period. Some animals lived longer in each experiment. Administration of calcium mesotartrate and vitamin K5 resulted in a smaller increase in body weight than in controls, with a definite prolongation of survival in some animals.
