Abstract
In order to elucidate the mechanism of plasma cholesterol reducing action by Shiitake mushroom (Lentinus edodes) or eritadenine (plasma cholesterol lowing substance in Shiitake), the levels of lipidsin plasma and liver, and the composition of plasma lipoproteins were studied in rats.
Plasma lipids and plasma lipoprotein levels were decreased by feeding of Shiitake and eritadenine, although, liver lipids levels were increased. In particular, α-lipopratein in plasma was decreased by eritadenine. The results suggest that the reduction of plasma cholesterol level by eritadenine may due to the decrease of plasma α-lipoprotein.
