Abstract
The effect of age and vitamin A on the change of collagen of skin and tail tendon in rats were studied.
The content of acid soluble collagen of tail tendon was decreased with age but acid insoluble collagen, on the contrary, increased in the older rats. Similar effect was seen in the vitamin A deficient rats.
It was observed in the skin of rats that fibrillar density of connective tissue, or hexosamine/hydroxyproline ratio was decreased with age and with vitamin A deficiency.
