Abstract
It was suggested that the liquid culture of Saccharomyces cerevisiae had the serum cholesterol-lowering effect. In order to confirm this result, the serum cholesterol level was measured by Sperry-Webb's method on mouse fed the control and experimental diets. The total serum cholesterol level in mouse fed the experimental diet was, on the average, 30% lower than the level in mouse maintained with the control diet. The change of total cholesterol was caused by the change the cholesterol ester. The change on serum cholesterol level by the exchange of the control and the experimental diets was discussed. Upon changing from the control diet to the experimental diet, serum cholesterol level decreased by approximately the same amount of starting. These changes were completely reversible.
Simultaneously, they were discussed the changes on serum protein, lipoprotein, GOT and GPT activities. The serum of mouse fed the experimental diet contained more total protein and less lipoprotein than the control. There were not very much changes on GOT and GPT activities between the control and the experiment.
