Abstract
The development of seborrhea was produced in rats fed the basal diet containing 10% or 15% of oleyl oleate, squalene and squalane.
(1) The chemical properties, TLC, IR and GLC analysis of lipid in skin and liver of rats which had developed seborrhea by feeding oleyl oleate were performed.
As the result, there was the presence of oleyl oleate in every lipid. Oleyl oleate was mainly contained in methanol insoluble part when lipid was treated by methanol.
(2) When rats were switched to the adequate diet containing ethyl linoleate from oleyl oleate, the alleviation of seborrhea symptom was observed.
(3) Squalene was contained in skin lipid of rats which had occurred seborrhea by giving squalene.
(4) When rats were switched to the commercial stock diet from squalane, the alleviation of seborrhea symptom was gradually observed.
