神経治療学
Online ISSN : 2189-7824
Print ISSN : 0916-8443
ISSN-L : 2189-7824
シンポジウム16:MGに対する薬物療法の最前線
重症筋無力症における有害事象を考慮したステロイド(経口,パルス療法)の使用
杉本 太路山脇 健盛越智 一秀郡山 達男
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2021 年 38 巻 4 号 p. 590-593

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Steroids are one of the primary therapies for myasthenia gravis (MG) patients. Oral or intravenous pulse administration of steroids should be recognized as having different effects on MG. Intravenous methylprednisolone therapy (IVMP) is used in the early stage as a fast–acting treatment. Oral steroids should be kept to small doses because higher and longer steroid treatments do not ensure better outcomes. Initial exacerbation induced by IVMP is a possible event, but IVMP considering the characteristics of effects and the adverse event can lead to improvement of symptom. In this review, effective steroid use, mainly IVMP, and its adverse events will be discussed.

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