脳腫瘍の最新治療

抄録

Brain tumors encompass a diverse group of intracranial neoplasms affecting not only the brain parenchyma but also the meninges and cranial nerves. This inherent heterogeneity translates into a multitude of tumor types, each with distinct treatment modalities. While advancements in molecular diagnostics have refined tumor classification, optimal treatment strategies continue to evolve.

This article delves into the complexities of central nervous system (CNS) malignancies before exploring treatment options. First, the unique immunological and anatomical properties of the CNS, often referred to as “organ specificity,” are discussed. This is followed by an examination of the significance of surgical intervention for tumors deemed unresectable with curative intent. Subsequently, the role of radiation chemotherapeutic approaches is addressed. Finally, leveraging this foundational knowledge, the article explores the recent strides made in glioma therapy guided by molecular biological markers.

By elucidating these aspects, this work aims to provide a comprehensive framework for understanding the challenges and advancements in brain tumor treatment within the burgeoning field of molecular diagnostics.