Japanese Journal of Oral Diagnosis / Oral Medicine
Online ISSN : 2188-2843
Print ISSN : 0914-9694
ISSN-L : 0914-9694
Clinical Reports
Wisdom Tooth Extraction without an Interruption of Warfarin Therapy in a Patient with Protein S Deficiency
SEIGO OHBAHITOSHI YOSHIMURAKAZUO SANO
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2014 Volume 27 Issue 2 Pages 197-201

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Abstract
Protein S deficiency (PSD) inhibits the anticoagulation response, requiring PSD patients to use anticoagulants such as warfarin. Various methods have been used before and after surgery to prevent postoperative complications such as bleeding and thrombus formation in PSD patients. A 62-year-old female PSD patient receiving warfarin underwent wisdom tooth extraction as an outpatient without interrupting her warfarin therapy. At the time of the surgery, the patient's prothrombin time/international normalized ratio (PT-INR) was 2.56. She was discharged to home wearing a surgical acrylic splint (SAS) for hemostasis and exhibited no postoperative complications. Use of the SAS allows PSD patients to safely undergo minor oral surgery, including tooth extraction, as an outpatient without interrupting their warfarin therapy.
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© 2014 The Japanese Society of Oral Diagnosis / Oral Medicine
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