2014 Volume 27 Issue 3 Pages 253-256
We herein report a case of a granular cell tumor arising from the dorsal side of the tongue in a 45-year-old female. The patient had noticed a mass on the left dorsal side of the tongue seven months earlier, but had ignored it as it was painless. The lesion exhibited a hard, elastic, clear boundary measuring approximately 15 × 15 mm on the left side of the back of the tongue. A biopsy was performed, and the lesion was diagnosed as a granular cell tumor. The tumor was resected, including the surrounding normal tissue. Histopathologically, it consisted of uniform cells with many eosinophilic granules in the cytoplasm and pseudoepitheliomatous hyperplasia. On immunohistochemistry, the cytoplasm and nucleus displayed immunoreactivity for S-100 protein and CD68. No evidence of any local recurrence was observed during the one-year follow-up period.
