2014 Volume 27 Issue 3 Pages 257-261
The incidence of malignant lymphoma has recently increased and it is becoming more common to encounter multiple primary carcinomas including the present case. In a case with multiple primary carcinomas with malignant lymphoma, it is necessary to determine the priority and treatment plan according to the clinical stage and the prognosis of the diseases. We therefore report a case with multiple primary carcinomas of the mandibular gingiva complicated by malignant lymphoma. Patient: 75-year-old male. Chief complaint: fecal occult blood. The patient visited the department of gastrointestinal medicine due to fecal occult blood in December 2006. A biopsy was conducted because the endoscopy revealed adenomatoid lesion. Consequently, the patient was diagnosed with diffuse large B-cell lymphoma and was transferred to the department of hematology to receive R-COP therapy. After two courses of the chemotherapy, an ulcerative lesion was detected on the buccal gingiva of the lower left molars in February 2007, which was diagnosed as squamous cell carcinoma of the mandibular gingiva (T2 N0 M0) by pathological examination, CT and MRI. Subsequently, marginal resection of the mandible was performed. Three months after the operation, four courses of R-COP therapy were conducted.
