Abstract
Introduction: Intracystic injection of OK-432 is reportedly effective in the treatment of cystic diseases such as ranula; however, only a few facilities perform this treatment modality. We herein report our experience of performing intracystic injection of OK-432 for cystic diseases in the head and neck area with favorable outcomes.
Subjects: The subjects were 50 patients treated with intracystic injection of OK-432 in the Department of Oral Surgery, Nishiarai Hospital, between January 2005 and March 2014.
Methods: (1) Diluent replacement: The contents of the cyst are aspirated as much as possible, and OK-432 solution diluted to the same volume as that of the aspirate is injected. (2) High-concentration injection: A solution containing OK-432 is injected at a high concentration without aspiration of the contents of the cyst. (3) Aspiration-injection procedure: The contents of the cyst are aspirated as much as possible, and OK-432 dissolved in 2-4 mL of physiological saline is injected.
Results: The treatment was effective in 47 (94%) of the 50 patients. No serious adverse reaction was observed.
Conclusion: Intracystic injection of OK-432 is a treatment modality that can be performed safely on an outpatient basis.
