Journal of Japanese Society of Oral Implantology
Online ISSN : 2187-9117
Print ISSN : 0914-6695
ISSN-L : 0914-6695
A Clinical and Histological Case Study using Bone Substitute Materials into Subantral Augmentation
Part 1. OsteoGen™ and Dembone™(mixed 7:3 Wt%)
Takeo SadanagaTakao Watanabe
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JOURNAL FREE ACCESS

1993 Volume 6 Issue 2 Pages 231-236

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Abstract

Several kinds of substitute bone materials have been used for subantral augmentation.
In this case report, the subantral augmentation material composed of resolvent hydroxyapatite (OsteoGen™ Impladent, Int.) and demineralized human bone (Dembone™ Pacific Cost Tissue Bank), which were mixed 7:3 by weight percent, was implanted and the specimen was biopsied from patient's buccul side of sinus floor with implanted material.
In the histological findings 6 months after implantation, newly formed bone tissue was observed surrounding the implanted granule at the light microscopic level. Dembone was not identified in this specimen. On the other hand, OsteoGen™ was surrounded with newly formed bone tissue, but some granules were adjacent to the macrophage-like giant cells without an inflamatory reaction. The resolving appearence on OsteoGen™ granules could not be recognize.
This formation of new bone seems to be produced by the osteoinductive material BMP in Dembone™ and“osteogenic space” of patient's proper bone.

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© 1993 Japanese Society of Oral Implantology
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