Abstract
Several kinds of substitute bone materials have been used for subantral augmentation.
In this case report, the subantral augmentation material composed of resolvent hydroxyapatite (OsteoGen™ Impladent, Int.) and demineralized human bone (Dembone™ Pacific Cost Tissue Bank), which were mixed 7:3 by weight percent, was implanted and the specimen was biopsied from patient's buccul side of sinus floor with implanted material.
In the histological findings 6 months after implantation, newly formed bone tissue was observed surrounding the implanted granule at the light microscopic level. Dembone was not identified in this specimen. On the other hand, OsteoGen™ was surrounded with newly formed bone tissue, but some granules were adjacent to the macrophage-like giant cells without an inflamatory reaction. The resolving appearence on OsteoGen™ granules could not be recognize.
This formation of new bone seems to be produced by the osteoinductive material BMP in Dembone™ and“osteogenic space” of patient's proper bone.
