Abstract
We consider arterial injection chemoradiotherapy as a potential option, and present a case wherein superselective intra-arterial chemoradiotherapy via bilateral superficial temporal arteries was effectively used against hard plate cancer.
A 63-year-old female was enrolled in our hospital with the chief complaint of a mass in her left palate gingiva. The mass measured 35×30mm, and had advanced from the left palate gingiva to the median region of the palate. No metastasis to the cervical lymph node was observed. She was pathologically diagnosed with squamous cell carcinoma based on the findings of a biopsy. We scheduled her for arterial injection chemoradiotherapy with the expectation of preserving the function and form of the oral and maxillofacial area. We placed catheters in both maxillary arteries close to both the superficial temporal arteries. Anticancer drugs were given in divided doses to the right and left sides at a ratio of 1：1, with a total dosage of DOC：60mg/m2 and CDDP：125mg/m2. The total radiation dose provided was 50Gy/25fr/5 weeks. Hematopoietic disturbance was observed after treatment initiation and we discontinued the therapy after 5 weeks. It has been 6 years since the patient underwent this therapy, and no recurrence or metastasis has been observed.
