Abstract
Mandibular metastasis of hepatocellular carcinoma is relatively rare. Here, we report a case of metastasis of hepatocellular carcinoma to the mandibular bone, who was treated with radical resection to preserve and maintain quality of life （QOL）. An 80-year-old man was referred to our hospital due to swelling in the right molar region of the mandible. Medical history revealed hepatic cell carcinoma （HCC） and bladder cancer. A painless and elastic swelling measuring 33×24mm with normal mucosa was observed in the right molar region of the mandible. Computed tomography showed a round osteolytic lesion in the mandible. A diagnosis of metastatic tumor from HCC was made based on pathological examination of a biopsy specimen. The primary HCC had not been completely controlled. However, severe pain and difficulty in eating appeared with the sudden increase in tumor size after biopsy. Moreover, metastatic foci other than the mandibular bone were not evident. Therefore, selective neck dissection and segmental mandibular resection followed by reconstruction with a titanium plate and pectoral major musculocutaneous flap was carried out to preserve and maintain oral function and QOL. The patient survived 20 months after the surgery without recurrence of mandibular tumor or any cosmetic and oral functional problems.
