Abstract
Adenoid cystic carcinoma is reported as a tumor having unfavorable prognosis, because it is localy more invasive than other malignant tumors and has clinical potential for recurrence and metastasis. Concerning the treatment of this tumor, complete excision with surgery is the preferred treatment, because adenoid cystic carcinoma is not a radiosensitive tumor and the chemotherapy is not a effective treatment for this tumor. Therefore, in the intensive case of this tumor, that is unresectable, a definitive treatment is sometimes difficult.
On the other hand, the hyperthermia treatment for the malignant tumor has attracted much attention recently. This therapy has strict antitumor effect by itself as well as the synergistic effect with radiotherapy and chemotherapy, especially against the malignant adenomas.
In this report, we present a case of large adenoid cystic carcinoma affected the whole maxillaly sinus treated by combination therapy with irradiation, chemotherapy, surgical excision and hyperthermia therapy and gained a fair prognosis.
