Abstract
Fourteen oral squamous-cell carcinomas with histological skin invasion, which had undergone curative resection, were investigated. The primary carcinomas were distributed throughout various sites in the oral cavity. All the skin which was invaded by the carcinoma was covering the site of the primary, primary recurrence or the metastatic lymph node.
A recurrence after surgical resection was noted in 7 out of the 14 patients. A recurrence with satellitosis was observed in 5 of the 7 cases, and all 5 of these patients died from failure of the primary focus control. It is assumed that satellitosis of the carcinomas might have resulted from retrograde lymphatic metastasis. It remains unclear whether radiation therapy or chemotherapy with the surgical precedure was effective in controlling the satellitosis. The accumulated 3-and 5-year survival rates of the 14 cases were 64.3 % and 35.7 %, respectively. It is suggested that the oral squamous cell carcinomas with the skin invasion should be resected as soon as possible before the incidence of satellitosis.