Abstract
Morphine has a powerful analgesic effect, but has no ceiling effect. Therefore, it is possible to administer morphine to advanced cancer patients with severe cancer pain until the pain is relieved.
A case of cancer pain management of an advanced adenoid cystic carcinoma patient who was administered a high dose of controlled-release Oral Morphine Sulfate at the outpatient clinic was reported. When morphine was administered increasingly until relief of cancer pain was obtained without causing serious side effects, the dosage of morphine became 2760 mg/day maximum and the duration of administration was twenty-one months. It was useful for improvement of the patient's quality of life to administer a high dose of controlled-release Oral Morphine Sulfate.