アンギオテンシンII受容体拮抗薬が誘因と推察された舌・口底部の血管性浮腫の1例

抄録

We report a case of angioedema in the tongue and oral floor potentially induced by angiotensin II receptor blockers (ARB).
A 77-year-old woman with a history of hypertension was treated with an ARB, and edematous lesions in the tongue and oral floor suddenly occurred about one week after the start of the treatment. She visited an emergency hospital, and was prescribed serrapeptase, a complex of betamethasone and chlorpheniramine maleate, and epinastine hydrochloride. But since the edema was poorly controlled, she was referred to our department. The ARB was strongly suspected to have caused the angioedema, so we stopped the ARB that she was taking. Edema disappeared one day after the onset of symptoms, and there has been no recurrence of symptoms after the termination of ARB treatment.