The objectives of report were: 1) to identify the guidelines for the management of patients on antithrombotic therapy requiring dental extraction; 2) to summarize the evidence and recommendations; and 3) to provide guidance for the dentists on identifying which patients can be managed in primary care.
We searched systematically for literatures in several electronic databases, focusing on dental surgery in patients receiving continuous antithrombotic therapy.
The following evidence-based recommendations were organized; (1) for patients within the stably therapeutic range of International Normalized Ratio (INR: 2.0-3.5), anticoagulant therapy continued for dental extraction with appropriate local haemostatic measures. (2) A check INR is recommended 72 hours prior to dental extraction. (3) It is not necessary to interrupt low-dose aspirin therapy (100mg/day or less) for dental extraction.